Postdoctoral Researcher - Goel Laboratory

Date:  24 Jul 2025
Site:  VCCC (Parkville)
Location: 

MELBOURNE, VIC, AU, 3000

Company:  Peter MacCallum Cancer Centre
Unit:  Goel
Division:  Cancer Research
Department:  Laboratory Research
Enterprise Agreement:  Allied Health Professionals (Victorian Public Sect
Goel

At Peter Mac we aim to continuously improve cancer care, research and education across all cancers and for all people affected by cancer: changing lives, breaking new ground. Everything we do is underpinned by our core values, Excellence, Compassion and Innovation. Welcoming people from a wide variety of different backgrounds and experiences is critical to fostering innovation, cultivating compassion, attracting and retaining top talent and providing the best possible cancer care for our patients.

 

YOUR ROLE IN OUR FUTURE

 

Postdoctoral Researcher - Goel Laboratory

  • 24-months fixed term, full time
  • 80 hours per fortnight with monthly ADOs
  • Attractive salary packaging options are available

 

About the team

The Goel Lab at the Peter MacCallum Cancer Centre and The University of Melbourne is seeking applications for a postdoctoral research scientist. Supported by a prestigious Snow Medical Research Fellowship (AUD $8 million, 2022-2030) and a US Dept of Defense Era of Hope Scholar Award (USD $3 million, 2024-2028), the Goel Lab is intently focused on addressing fundamental unanswered questions relating to tumour dormancy and therapy-induced senescence in cancer. As a Postdoctoral Research Fellow, the successful candidate will be key to the success of projects pertinent to these themes, leveraging the lab’s expertise and suite of purpose-built, novel in vitro and in vivo models.

Under the direction of A/Prof Shom Goel, a medical oncologist and laboratory head, the Goel Lab positions itself at the intersection of cell cycle biology, epigenetics, and tumour immunology in cancer. Specifically, we study the cell cycle machinery and how it influences cancer biology in both cancer cells and stromal cells and leverage our discoveries to design new drug therapies for cancer.

We have developed several new transgenic mouse models of cancer which have proven valuable for uncovering new mechanisms of drug activity, and our work has been published in high-impact journals including Nature (2017), Cancer Cell (2016), Cancer Discovery (2024), and Nature Cancer (2021). Importantly, several of our discoveries have translated into large-scale clinical trials.

 

About the role

The position will have a focus on the continuation of important work in therapy induced senescence using lineage tracing as well as other related work in this space. This position is responisble for:

  • Competently carrying out experiments that fulfill the aims of the project
  • Accurate analyisis and interpretation of experiment results
  • Writing and leading the publication of scientific papers
  • Leads appropriate research-based grant and fellowship applications
  • Participation and presentation in discussions and lab meetings

 

The successful applicant will hold a PhD in cancer biology and therapeutics with a focus on cell cycle biology. It is essential that the candidate has a strong track record in cancer research exemplified by a broad knowledge of cancer biology.

 

This position is:

  • Fixed term, full time
  • Onsite presence essential at 305 Grattan Street, Melbourne, VIC 3000
  • Basic Salary Range: $99,725.81 to $115,527.48 AUD
  • Advertising from 24 July 2025 to 21 August 2025

 

Our benefits

We offer a range of benefits which support our people both personally and professionally, including:

  • Up to $11,660 in salary packaging to increase your take home pay
  • Discounted health insurance and eye care
  • A comprehensive health and wellbeing program
  • Public transport options at our doorstep and end of trip facilities for cyclists
  • Onsite eateries and coffee shops and inviting rooftop garden spaces
  • Pathways for professional development and new career opportunities
  • Five weeks annual leave, 17.5% leave loading, purchased leave options and monthly ADO’s

 

Inclusion and belonging

Peter Mac celebrates, values and supports a diverse and inclusive environment which reflects our vibrant community. We encourage applications from anyone identifying as Aboriginal and/or Torres Strait Islander. We also welcome anyone who identifies as LGBTQIA+, linguistically, culturally and/or gender diverse, people with disability, and people of any age to apply for our roles.

 

Join us!

If you feel this role is right for you we warmly invite you to apply, and encourage your early application. All appointments are made subject to a satisfactory police check and may include vaccination requirements. Should you need assistance or require any adjustments or accommodations to fully participate in the application or interview process, you are welcome to reach out to the contact person listed. We acknowledge that not all applicants will meet the full list of selection criteria outlined, and wherever possible we will consider applications where relevant experience can apply.

 

Applicants to this role should provide a covering letter outlining relative key skills and experience to assist us with our assessment.

For further information about this opportunity, click Apply to be redirected to the Peter Mac Careers page where you can review the position summary. Alternatively, please contact us using the information below for a confidential discussion.

 

Hiring Manager: Shom Goel

Contact Number: (03) 8559 8777

Email: Shom.Goel@petermac.org

 

Applications Close: 21 August 2025
______________________________________________________________________________________________________

Position Summary

The Postdoctoral Research Fellow is responsible for running projects under the direction of A/Prof Shom Goel, a medical oncologist and laboratory head. The role is essential for not only high-quality research but also communicating this effectively to the scientific community, leading grant applications and supporting the next generation of researchers by supervising and mentoring students. The Goel Lab positions itself at the intersection of cell cycle biology, epigenetics, and tumour immunology in cancer. Specifically, we study the cell cycle machinery and how it influences cancer biology in both cancer cells and stromal cells and leverage our discoveries to design new drug therapies for cancer. We have developed several new transgenic mouse models of cancer which have proven valuable for uncovering new mechanisms of drug activity, and our work has been published in high-impact journals including Nature, Cancer Cell, Cancer Discovery, and Nature Cancer. Importantly, several of our discoveries have translated into large-scale clinical trials. At present, the Goel lab is focused on addressing some of the fundamental unanswered questions relating to tumour dormancy and therapy-induced senescence in cancer.

As this position is tied to a Fellowship from the Cancer Council Victoria until 2026, it is expected that the incumbent overseas all the associated aims and milestones for this, with a particular focus on “Targeting Dormant Metastatic Cells to Prevent Recurrence of Breast Cancer”. Success in this role is dependent on a high level of communication related to progress and outcomes of the associated projects. 

Enterprise Agreement

Allied Health Professionals Enterprise Agreement

Classification or Salary Range

1RA6 - 1RA10

Immunisation Risk Category

Category A: Position involving direct patient contact, potential for exposure to blood, body fluid, human tissue specimens during course of a normal working day
 

Key Relationships

Internal
  • Supervisor: A/Prof Shom Goel
  • Goel lab staff and students
  • Cancer Biology and Therapeutics Program 
  • Other research laboratory staff and students
  • Core research facilities staff and students
  • Other Peter Mac staff and students
External
  • Staff from other research institutions and hospitals
  • External collaborators
  • Suppliers

 

Education

Skills

Essential Requirements
  • PhD in Molecular or Cell Biology
  • Strong track record in cancer research exemplified by a broad knowledge of cancer biology
  • Ability to work well within a research team exemplified by collegiality, diligence, and accountability
  • Technical and advanced experience in cancer epigenetics  
  • Extensive experience with cell biology techniques including cell culture, conducting cell-based assays in vitro (i.e. cell counting, drug treatments), generation of retrovirus and lentivirus
  • Experience with molecular biology techniques including western blotting; extraction of DNA, RNA, and protein from cells; PCR; RT-qPCR and CRISPR
  • Experience working with laboratory mice including animal handling, oral gavage, mouse anaesthesia, and survival surgery
  • Excellent written and oral communication skills
  • Flexibility, ability to develop new skills and work with feedback
  • High level organizational and time management skills, including punctuality
  • Ability to keep abreast of the relevant scientific literature whilst carrying out laboratory work, and to integrate these tasks to develop new scientific questions to be addressed in the lab
Desirable Requirements
  • Experience with bio-informatic analysis of RNA-seq, ATAC-seq, and ChIP-seq datasets
  • Outstanding academic track record
  • Desire to pursue cancer research long-term
  • Experience with digital image analysis including Image J
  • Basic programming skills using R, Python, Unix terminal
  • Basic knowledge of principles of data interpretation including statistical analysis
  • Spatial transcriptomics analysis

 

Certifications, Licenses & Registrations

Key Accountabilities

Key Accountabilities Demonstrated by / Key Performance Indicators
1. Conduts rigorous, valid and ethical research both independently and as part of the laboratory team
  • Competently carries out experiments that fulfil the aims of the projects
  • Excellent technical skills and eye for detail 
  • Accurate analysis and interpretation of experiment results 
  • Willingness to learn and follow instructions
  • Ability to work independently 
  • Regularly demonstrates proactive and innovative thinking engaging with the group leader and laboratory in the pursuit of excellence
  • Regular attendance and contribution at group and program meetings 
  • High level of integrity and ethics 
  • Complete tasks in a timely and efficient manner
  • Excellent record-keeping skills
2. Communication of research outcomes
  • Writes and leads the publication of scientific papers
  • Presentation of research results at lab meetings
  • Participation in discussions, lab and program meetings 
  • Ability to communicate effectively with others in the laboratory as well as the broader scientific community
  • Excellent oral and written communication skills
3. Input into the administrative and management functions of the laboratory, including supervision of staff and students
  • Contributes to discussions, lab, hub and program meetings
  • Provides help and regular feedback to staff and students
  • Participates in multi-directional mentorship
  • Leads appropriate research-based grant and fellowship applications
4. Fosters good working relationships with colleagues
  • Excellent working relationships with others both within the laboratory and within the broader community in health and science
  • Ability to work in a team 
  • Proactively pursues relevant collaborations and manages these relationships effectively to reach shared goals
  • Willingness to help others in lab as required

 

Key Accountabilities (Contd..)

______________________________________________________________________________________________________

 

For further information about this opportunity, click Apply to be redirected to the Peter Mac Careers page where you can review the position profile. Alternatively, please contact us for a confidential discussion.

 

 

Peter Mac is a child safe organisation and has a commitment to child safety and wellbeing.

 

 

WHY WORK FOR PETER MAC

 

  • Peter Mac offer a range of benefits which support our people both personally and professionally.
  • Our staff benefits include award winning facilities, professional development and events, a health and wellbeing program, flexible work practices and policies and financial benefits such as salary packaging.
  • We encourage applications from Aboriginal and Torres Strait Islander people, all members of the LGBTQI community and people with a disability.